In this conversation, Paul Adepoju hosts Alukhethi Singo-Ragimana from MGI Tech. They discuss the unique features of MGI’s sequencing technology, its applications in HIV genotyping and drug resistance surveillance, and the challenges and solutions in the sequencing ecosystem in Africa. They also talk about MGI’s plans for South Africa and its involvement in the Africa-wide genomic initiative. The conversation highlights the affordability and competitiveness of genomic sequencing technologies, the impact of the COVID-19 pandemic on sequencing adoption, and the potential of sequencing to transform healthcare in Africa.